QUANTITATIVE PREDICTION OF HUMAN PHARMACOKINETICS AND PHARMACODYNAMICS OF CKD519, A POTENT INHIBITOR OF CHOLESTERYL ESTER TRANSFER PROTEIN (CETP)

Quantitative Prediction of Human Pharmacokinetics and Pharmacodynamics of CKD519, a Potent Inhibitor of Cholesteryl Ester Transfer Protein (CETP)

CKD519, a selective inhibitor of cholesteryl ester transfer protein(CETP), is undergoing development as an oral agent for the treatment of primary hypercholesterolemia and mixed hyperlipidemia.The aim of this study was to predict the appropriate efficacious dose of CKD519 for humans in terms of the inhibition of CETP activity by developing a CKD519

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Circular Economy as an Important Lever to Reduce Greenhouse Gas Emissions: Case of an Electricity Distribution Company in Morocco

This article discusses the major challenges related to greenhouse gas (GHG) emissions in the electricity sector and their impact on global climate change.The electricity sector is responsible for about a quarter of total global GHG emissions.To address these challenges, Life Cycle Assessment (LCA) is used to measure the environmental impact of diff

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Surgical and Functional Outcome of Laparoscopic Vaginal Suspension Combined with Suture Rectopexy for Management of Pelvic Organ Prolapse

Purpose Laparoscopic techniques to treat pelvic organ prolapse are gaining popularity around the globe due to their low recurrence Keyboard Accessories rates and better functional results compared to perineal techniques.However, the optimum surgical procedures are not yet determined.In the current research, we suggest a novel surgical approach, lap

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